Transparency

Formula 01 ingredients: what is in this 2-DDR scalp serum

Six actives at stated levels in a fragrance-free alginate gel, each chosen for scalp vitality, moisture, surface nourishment or the appearance of hair density and fullness. Expand any ingredient to see what it is and the job it does.

Formula 01 is formulated for visibly thicker-looking, fuller-looking, denser-looking hair, and designed to support a revitalized, healthy-looking scalp environment. It is a cosmetic: nothing on this page is a medical claim for the product or any ingredient in it.

The formula, ingredient by ingredient

2-Deoxy-D-Ribose Core ingredient

Level in formula: 2.5%

2-deoxy-D-ribose (2-DDR) is a simple five-carbon sugar, best known as the sugar in the backbone of DNA. It is the core ingredient of Formula 01, at a high stated 2.5%, and the reason Formula 01 is a 2dDR serum for fuller-looking, denser-looking hair. It dissolves in water, which lets it sit in the alginate gel base. It is a reducing sugar, so the formula pairs it with sodium phytate. More: what is 2-DDR?

Niacinamide Scalp conditioning

Level in formula: 3.0%

Niacinamide is the amide form of vitamin B3. It is one of the most widely used conditioning ingredients in leave-on skin and scalp products. In Formula 01 it conditions the scalp and provides moisture barrier support, for a comfortable, healthy-looking scalp surface.

Caffeine Skin conditioning

Level in formula: 1.5%

Caffeine is the familiar compound from coffee and tea leaves, used in cosmetics as a skin-conditioning ingredient. It appears often in scalp products. Formula 01 uses it at 1.5%, alongside adenosine at 0.75%, for a revitalized-looking scalp.

Panthenol Humectant and conditioning

Level in formula: 1.0%

Panthenol is provitamin B5. It is a humectant, meaning it holds water, and a conditioning ingredient used across hair and skin care. It brings surface nourishment and moisture to the scalp and the hair at the root, and promotes the appearance of stronger-looking, more resilient strands.

Adenosine Skin conditioning

Level in formula: exactly 0.75%

Adenosine is a small molecule made of adenine joined to ribose, used in skin and hair care as a conditioning ingredient. Formula 01 uses exactly 0.75%. That level matches established use in hair-care products and was chosen deliberately, not rounded up for the label. It conditions the scalp alongside caffeine.

Melatonin Skin conditioning

Level in formula: 0.10%

Melatonin is a small molecule used in cosmetics as a skin-conditioning ingredient. Formula 01 uses 0.10%, the smallest of the stated active levels, as part of its scalp-conditioning complex.

Sodium Alginate Gelling agent

Level in formula: gel base

Sodium alginate comes from brown seaweed. It holds water to form a soft gel, which gives Formula 01 its thick texture, then dries to a light film on the scalp. No sodium chloride, zinc or copper salts are added to thicken the gel. More: why an alginate gel.

Sodium Phytate Chelating agent

Level in formula: 0.10%

Sodium phytate is the sodium salt of phytic acid, a compound found in plant seeds. It is a chelating agent: it binds stray metal ions such as calcium and magnesium so they do not disturb the alginate gel, and it supports the preservative system.

Ethylhexylglycerin Preservative synergist

Level in formula: 0.10%

Ethylhexylglycerin is a glycerin-derived ingredient used with preservatives to support them, and as a skin-conditioning ingredient.

Questions about the complete ingredient list in label order (INCI): email contact@synergy45.com.

How to read this page

Each entry says what the ingredient is and its role in the formula, using standard cosmetic ingredient functions such as conditioning, humectant or chelating agent. The percentages are the levels stated for Formula 01.

The overall formula is the result of 45 reformulations and two years of organic chemistry and applied biology work, made in small batches. It is a cosmetic, designed for how the scalp and hair look and feel, and it is not a treatment for any medical condition.

See the 2.5% 2-DDR serum

Cosmetic vs drug

Formula 01 is a high-concentration 2-Deoxy-D-Ribose (2dDR) cosmetic scalp serum for fuller-looking hair, designed to support a revitalized, healthy-looking scalp environment.

It is not a drug. It is not intended to diagnose, treat, cure, or prevent any disease. For any scalp or hair concern, talk to a dermatologist.

Written and reviewed by Synergy45 · Last reviewed: October 2026
Related pages:
Formula 01 directions